PubMed.gov
PubMed.gov is the US National Library of Medicine Nation Institutes of Health. Pubmed comprises more than 24 million citations for biomedical literaturs from MEDLINE, life science journals, and online books.…
Cannabidiol: promise and pitfalls.
Abstract: Over the past few years, increasing public and political pressure has supported legalization of medical marijuana. One of the main thrusts in this effort has related to the treatment…
Blurred boundaries: the therapeutics and politics of medical marijuana.
Abstract: For 5 millennia, Cannabis sativa has been used throughout the world medically, recreationally, and spiritually. From the mid-19th century to the 1930s, American physicians prescribed it for a plethora…
Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation
Abstract: The emerging potential for the cannabinoid (CB) system in modulating gastrointestinal inflammation has gained momentum over the last few years. Traditional and anecdotal use of marijuana for gastrointestinal disorders,…
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.
Abstract: Delta(9)-Tetrahydrocannabinol (THC) exhibits antitumor effects on various cancer cell types, but its use in chemotherapy is limited by its psychotropic activity. We investigated the antitumor activities of other plant…
The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent.
Abstract: Anandamide is a lipid neurotransmitter which belongs to a class of molecules termed the endocannabinoids involved in multiple physiological functions. Anandamide is readily taken up into cells, but there…
Cannabis—A Valuable Drug That Deserves Better Treatment
Abstract: About 150 years ago, a French psychiatrist, J. J. Moreau, conducted a novel clinical experiment in which he administered hashish to humans. His volunteers, including Moreau himself, experienced “occurrences…
Cannabis Use and Risky Behaviours and Harms: A Comparison of Urban and Rural Populations in Canada
Abstract: Cannabis is the most prevalent illicit substance used by Canadians 15 years of age and older (Health Canada, 2012a). Its use has been linked to a number of both…
The Inhibitory Effects of Cannabidiol on Systemic Malignant Tumors
Abstract: The recent article by Johnson et al.1 provided for highly stimulating reading. Cannabidiol may attenuate tumor growth in a number of other systemic malignancies. Decreased tumor growth in pulmonary…
Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol
Abstract: Purpose: Colon cancer is a major public health problem. Cannabis-based medicines are useful adjunctive treatments in cancer patients. Here, we have investigated the effect of a standardized Cannabis sativa…